Nuclear Medicine & Radiation Therapy

Department of Chemistry and Bioengineering, University of Harvard, Cambridge, MA 02138, USA

Publications

• Mini Review   
  Breast Cancer Detection and Diagnosis Using Radionuclide Techniques and Instruments
  Author(s): Léa Berland*
  
  The diagnosis and treatment of disease make use of radioisotopes of a wide variety of elements, the majority of which are metals, in nuclear medicine. A chelator that effectively forms thermodynamically and kinetically stable complexes with the metal ions' radioisotopes, or radiometals, is necessary for these applications. Additionally, the chelator attaches to a biological targeting vector to locate diseased tissues. While numerous chelators that are suitable for small radiometals have been developed, chelators that are effective for large radiometals are much less common. In this Report, we discuss recent developments in the development of ligands for the chelation of large radiometals, which have potential applications in nuclear medicine... Read More»
  DOI: 10.37421/2155-9619.2022.13.516

  Abstract HTML PDF