Fluid Mechanics: Open Access

Department of Civil Engineering and Architecture, Zhejiang University of Science & Technology, Hangzhou 310023, China

Publications

• Mini-Review   
  Mechanical Mechanism of Ion and Water Molecular Transport in Angstrom-Scale Graphene Derivative Channels: Atomic Model to Solid-Liquid Interaction
  Author(s): Lei Fan*
  
  Most marketed HA-based dermal fillers use chemical cross-linking to improve mechanical qualities and extend in vivo lifetime; nevertheless, stiffer formulations with greater elasticity necessitate a higher extrusion force for injection in clinical practise. To strike a balance between longevity and injectability, we suggest thermosensitive dermal filler that is injectable as a low viscosity fluid that gels in situ upon injection. In order to achieve this, HA was attached via a linker to poly (N-isopropylacrylamide) (pNIPAM), a thermosensitive polymer, using "green chemistry" and water as the solvent. At normal temperature, HA-L-pNIPAM hydrogels had a relatively low viscosity (G′ was 105.1 and 233 for Candidate1 and Belotero Volume, respectively) and spontaneously produced a stiffer gel with submicron structure at body temperature. Hydrogel compositi.. Read More»
  DOI: 10.37421/2476-2296.2023.10.284

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