Department of Medicine and Geriatrics, IBN Rochd University Hospital Center, Casablanca, MAR, Morocco
Review Article
The Management of ANCA-associated Vasculitis: We Only See the Tip of the Iceberg
Author(s): Chaïmaâ Zeroual*, Merieme Benzakour, Mina Moudatir, Khadija Echchilal, Leïla Barakat, Safaâ Mourabit and Hassan El Kabli
Antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) encompasses a group of rare autoimmune diseases affecting small
blood vessels, including granulomatosis with polyangiitis, eosinophilic granulomatosis with polyangiitis, and microscopic polyangiitis. Diagnosing
AAV relies on clinical, biological, radiological, and histological findings. Despite advancements in understanding and treating these conditions,
challenges remain in accurate prognosis and therapy management. The Five-Factor Score and Birmingham Vasculitis Activity Score are used to
evaluate disease severity and guide treatment decisions, yet these tools have limitations and may not fully capture disease complexity. Recent
epidemiological studies have highlighted the geographic variability in AAV incidence and the role of ANCAs as diagnostic and prognostic markers.
Treatment involv.. Read More»
DOI:
10.37421/2471-9544.2024.10.260
Journal of Vasculitis received 83 citations as per Google Scholar report