Department of Neurobiology and Genetic of Behavior, Witten/Herdecke University, Germany
Research
Neuropsychological Long Term Decline Related to Silent Cerebral Lesions after Pulmonary Vein Isolation
Author(s): Martina Piefke*, Lena Goldschmidt, Marc Horlitz, Buelent Koektuerk and Martin Bansmann
Objectives: In this study, we aimed at investigating putative neuropsychological long term impairments of cognitive flexibility, verbal long term memory, and theory of mind in patients with atrial fibrillation depending on frontal silent cerebral lesions 6-9 years after pulmonary vein isolation with a pulmonary vein ablation catheter. Background: The pulmonary vein ablation catheter (PVAC) shows an increased prevalence of developing silent cerebral lesions after pulmonary vein isolation in patients with atrial fibrillation. Methods: 20 participants were medically and neuropsychologically examined and underwent MRI of the brain. Results: Most lesions were located in the frontal lobes. Largeness of frontal lesions positively correlated with poorer verbal memory performance. Moreover, selective impairments of executive functions were associated with the extent of lesions. Symptom severit.. Read More»
DOI:
10.4172/2329-6895.10.4.487
Neurological Disorders received 1343 citations as per Google Scholar report