Department of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy
Mini Review
Rhenium Radioisotopes in Medicine: Manufacture and Uses
Author(s): Licia Uccelli*
The diagnosis and treatment of disease make use of radioisotopes of a wide variety of elements, the majority of which are metals, in nuclear
medicine. A chelator that effectively forms thermodynamically and kinetically stable complexes with the metal ions' radioisotopes, or radiometals,
is necessary for these applications. Additionally, the chelator attaches to a biological targeting vector to locate diseased tissues. While numerous
chelators that are suitable for small radiometals have been developed, chelators that are effective for large radiometals are much less common. In
this Report, we discuss recent developments in the development of ligands for the chelation of large radiometals, which have potential applications
in nuclear medicine... Read More»
DOI:
10.37421/2155-9619.2022.13.515
Nuclear Medicine & Radiation Therapy received 706 citations as per Google Scholar report