Department of Bioanalytical Sciences, Shanghai Henlius Biotech, Inc, Shanghai 210000, China
Review
A Review on LBA and LC-MS Platforms for Supporting Large Molecule Pharmacokinetics Bioanalysis
Author(s): Linglong Zou*, Xiaolong Zhang, Zhaoyang Zhang, Weiping Shao and Zhongping Lin
Over the past ten years, the global market for large molecule therapeutics has rapidly grown for the treatment of a variety of diseases. LBA and LC-MS are two platforms widely used in pharmacokinetic bioanalysis. In this review, we compare LBA and LC-MS and summarize their strengths and limitations. Strategies for platform selection are provided according to the study purpose, study phase, analyte types, assay requirements and other factors. .. Read More»
DOI:
10.37421/1948-593X.2020.12.227
Journal of Bioanalysis & Biomedicine received 3099 citations as per Google Scholar report