Department of Microbiology, Biochemistry and Immunology, Vasile Goldis Western University of Arad, 86 Rebreanu, Arad 310414, Romania
Mini Review
Exosomal Micrornas Derived from HIV-infected Macrophages
Author(s): Lisa Garrell*
Exosomes are extracellular vesicles that play crucial roles in intercellular communication by transporting various biomolecules, including
microRNAs (miRNAs). In the context of HIV infection, exosomes derived from infected cells, particularly macrophages, have gained attention
for their potential role in viral pathogenesis and immune modulation. This review focuses on exosomal microRNAs derived from HIV-infected
macrophages, exploring their biogenesis, composition, functional roles in viral persistence and immune evasion and potential as biomarkers or
therapeutic targets. Understanding the interplay between exosomal miRNAs and HIV pathogenesis can provide insights into novel strategies for
disease management and therapeutic intervention... Read More»
DOI:
10.37421/2168-9547.2024.13.440
Molecular Biology: Open Access received 607 citations as per Google Scholar report
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