Department of Medical Laboratory, Chongqing Liangjiang New Area People’s Hospital, Chongqing 401121, China
Case Report
Talaromyces Marneffei Infection Inducing Hemophagocytic Syndrome in an HIV-negative Adult Patient
Author(s): Liyi Hu*, Ling Liu*, Lunyu Yang, Yuling Yi, Taimei Duan, Dongmei Huang, Sitian Tang, Zhu Mei, Xinlu Bai, Xianping Luo and Yong Luo
Background: Talaromyces Marneffei (TM) infection is commonly seen in HIV-positive or immunocompromised patients but rarely reported in
HIV-negative individuals. Hemophagocytic syndrome is one of a group of syndromes characterized by overactivity of immune cells resulting in the
production of excessive inflammatory factors and causing damage to multiple organs.
Case presentation: This case report presents a previously healthy 52-year-old male patient who experienced persistent fever and chills for
over 20 days. Initial blood tests revealed decreased hemoglobin and platelets, and increased proportion of neutrophils. Laboratory examinations
showed elevated levels of procalcitonin, C-reactive protein, erythrocyte sedimentation rate, ferritin, along with abnormalities in liver function.
Imaging studies indicated hepatos.. Read More»
DOI:
10.37421/2165-7920.2024.14.1593
Journal of Clinical Case Reports received 1295 citations as per Google Scholar report