Library of Nantong University, Nantong University, Nantong 226019, China
Research Article
Chromosomal Distribution of Human Disease Genes
Author(s): Lucy L. Xu
It is necessary and useful to reveal the chromosomal distribution at whole-genome level. By studying the chromosomal distribution of human disease genes, we found that the known genes of single-gene diseases are significantly enriched in chromosome X, and depleted in 10p, 19q. And the genes of multi-gene diseases are significantly tended to be located in fewer chromosomes than random background. The chromosomal distribution at whole-genome level could promote future studies of human disease genes... Read More»
DOI:
10.37421/2155-6180.2022.13.91
Journal of Biometrics & Biostatistics received 3254 citations as per Google Scholar report