Department of Biology, Universidad del Valle, Cali 760042, Colombia
Mini Review
Genomic Insights into Antibiotic Resistance: Mechanisms and Countermeasures
Author(s): Lucy Maisie*
Antibiotic resistance poses a significant threat to global health, necessitating a deeper understanding of its genomic underpinnings. This review
explores various mechanisms by which bacteria acquire resistance genes, including mutations, horizontal gene transfer and mobile genetic
elements. Furthermore, it discusses genomic approaches such as whole genome sequencing and metagenomics that elucidate the spread and
evolution of resistance. Countermeasures against antibiotic resistance, such as novel drug development and precision medicine strategies
informed by genomics, are also highlighted. Integrating genomic insights into clinical practice promises to enhance surveillance, diagnosis and
treatment of resistant infections, thereby safeguarding public health... Read More»
DOI:
10.37421/2472-128X.2024.12.270
Journal of Clinical & Medical Genomics received 391 citations as per Google Scholar report