Journal of Clinical Case Reports

Department of Medicine, University of Verona, Verona, Italy

Publications

• Case Report   
  Efficacy of Anti-CD Monoclonal Antibody in SLE-Related Sneddon’s Syndrome with Anti phospholipid Antibodies and Interstitial Lung Disease: A Case Report
  Author(s): Delfino Lorenzo, Tinazzi Elisa, Olivieri Bianca, Todesco Mattia, Caminati Marco and Lunardi Claudio*
  
  Sneddon’s Syndrome (SS) is a rare condition characterized by a non-inflammatory thrombotic vasculopathy, which involves small and medium vassels. Cerebrovascular disease and livedo racemosa are the main clinical manifestations of this syndrome. The incidence of SS has been estimated of 4 cases per 1 million/year in general population with a high prevalence in young women between 20-40 years of age. Three forms of the syndrome have been described: idiopathic, without a clear causative factor, related to primary Antiphospholipid Syndrome and related to Systemic Lupus Erythematosus (SLE) with or without anti-phospholipid antibodies. To date, there are very few indications for diagnosis and treatment. Skin biopsy and brain MRI are considered fundamental in the diagnostic process; however histologic samples could be negative or non-specific. Current treatment is based on oral anticoa.. Read More»
  DOI: 10.37421/2165-7920.2020.10.1341

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