Department of Biomedical Technologies, Coburg University of Applied Sciences and Arts, Friedrich-Streib, Coburg, Germany
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Targeted Nanoparticle Delivery of CRISPR−Cas9 System for Precision Genome Editing In vivo
Author(s): Margherita Fogliano*
Precision genome editing holds immense promise for the treatment of genetic disorders, but efficient in vivo delivery of CRISPR-Cas9 components
remains a formidable challenge. This article explores the development and application of targeted nanoparticles as a delivery platform for the
CRISPR-Cas9 system. We discuss the design, optimization, and in vivo testing of nanoparticles tailored to specific cell types and tissues. The
integration of nanotechnology and genome editing not only enhances the precision and efficiency of genome modifications but also paves the way
for potential therapeutic breakthroughs... Read More»
DOI:
10.37421/1948-593X.2023.15.397
Journal of Bioanalysis & Biomedicine received 3099 citations as per Google Scholar report