Cancer Science & Therapy

Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK

Publications

• Review Article   
  Understanding the Role of Liquid Biopsies in the Early Detection of Breast Cancer
  Author(s): Arianna Zhu* and Maria Neofytou
  
  Breast Cancer (BC) remains a significant global health challenge, with early detection playing a crucial role in improving survival rates. Traditional detection methods such as mammography, MRI, and biopsies have limitations that impact the timely diagnosis of early-stage BC. This review focuses on the potential of liquid biopsies, specifically Circulating Tumor DNA (ctDNA) analysis, as a non-invasive alternative for early breast cancer detection. Liquid biopsies offer advantages in terms of non-invasiveness and the ability to be repeated over time, providing valuable insights into tumor genetics. However, current ctDNA assays face challenges, particularly in detecting early-stage cancers due to low ctDNA levels. The review examines recent advancements in ctDNA research, including the role of key genetic mutations and copy number alterations, and highlights the.. Read More»
  DOI: 10.37421/1948-5956.2024.16.662

  Abstract HTML PDF