Chemical Sciences Journal

Department of Biochemistry, Biomedical Research Foundation of the Academy of Athens, Athens, Greece

Publications

• Short Communication   
  Applications of Photonic Biosensor Device for Monitoring Cancer Treatment
  Author(s): Maria Scheres*
  
  In this article, we discuss the creation of a photonic biosensor device as an additional diagnostic tool for cancer treatment monitoring. To get around detection reliability, sensitivity, specificity, compactness and cost concerns, the suggested device incorporates multidisciplinary principles from the reader/packaging, nano-biochemical, micro-fluidic and photonic platforms. The sensing is done by measuring the phase shift of the output signal, produced by the binding of the analyte on the functionalized aMZI surface and the photonic sensor is based on an array of six asymmetric Mach Zender Interferometer (aMZI) waveguides on silicon nitride substrates. The waveguides' morphological design results in an improved sensitivity (5000 nm/RIU) in compared to earlier technologies. By combining this platform with a cutting-edge biofunctionalization technique that uses .. Read More»
  DOI: 10.37421/2150-3494.2022.13.300

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