Clinical and Medical Case Reports

Department of Paediatrics, Paediatric Immunology and Rheumatology Referral Center, Hippokration General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece

Publications

• Research   
  SLC8A1 Gene Polymorphism Rs13017968 and Hematological Parameters in Kawasaki Disease
  Author(s): Evdoxia Sapountzi*, Andreas Giannopoulos, Styliani Fidani, Maria Trachana, Fragiskos Bersimis, Spiros Gerou and Assimina Galli-Tsinopoulou
  
  Kawasaki disease, an acute inflammatory vasculitis, affects children <5 years old. Coronary artery aneurysms constitute a serious complication of the disease. Both genetic factors and hematological parameters (e.g., mean platelet volume-to-lymphocyte ratio) have been implicated in the development of Kawasaki disease and coronary artery aneurysms. We explored the role of rs13017968, a single nucleotide polymorphism in SLC8A1, and of the mean platelet volume-to-lymphocyte ratio in Kawasaki disease and coronary artery aneurysms. This single-center, case-control study included children with Kawasaki disease treated in our clinic and healthy children registered in the emergency unit. All patients received intravenous immunoglobulin upon diagnosis. Primary outcomes included rs13017968 frequency and the mean platelet volume-to-lymphocyte ratio in patie.. Read More»
  DOI: 10.37421/2684-4915.2023.7.265

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