Department of Epidemiology and Prevention, IRCCS NEUROMED, Pozzilli (IS), Italy
Research
Risk Factors for Atherothrombotic Disease and Lumbar Spinal Stenosis: Results from the PREFACE Study
Author(s): Emilia Ruggiero, Simona Costanzo, Augusto Di Castelnuovo, Mariarosaria Persichillo, Simona Esposito, Sara Magnacca, Ettore Carpineta, Chiara Cerletti, Marialaura Bonaccio, Maria Benedetta Donati, Sergio Paolini, Vincenzo Esposito, Giovanni de Gaetano, Gualtiero Innocenzi and Licia Lacoviello*
Background and aim: Atherothrombotic disease of feeding arteries of lumbar spine could be an underlying mechanism for Lumbar Spinal
Stenosis (LSS). We aimed at evaluating the association of a large panel of risk factors for atherothrombotic disease, alone or in combination, with
LSS in multivariable models.
Methods: Case-control study: 213 consecutive patients with LSS, eligible for surgery at the Neurosurgery Department of IRCCS Neuromed, were
enrolled in the PREFACE study; 426 controls, matched 1: 2 for sex, age (± 6 months) and physical activity, without a history or clinical evidence of
LSS were selected from the general population. Odds Ratios (ORs) and their 95% Confidence Intervals (CIs) were calculated using conditional-tomatch
(for age and sex) logistic regression.
Results: Manual occupa.. Read More»
DOI:
10.37421/2165-7939.2020.9.448
Journal of Spine received 2022 citations as per Google Scholar report