Cardiovascular Diseases & Diagnosis

Université de Sherbrooke Research Center, Sherbrooke, Canada

Publications

• Research Article   
  Troponin and Nt-pro-BNP Fluctuation During Hemodialysis and Impact on Cardiovascular Prognosis
  Author(s): Patrick Prud’homme*, Hajar El-Kamouni, Gabriel Fortin, Anne-Marie Côté, Mélanie Godin, Paul Farand, Serge Lepage, Thao Huynh and Michel Nguyen
  
  Introduction: Chronic elevation of high sensitivity troponin (hs-cTnT) and N-terminal brain-natriuretic peptide (Nt-pro-BNP) in end-stage renal disease is associated with worse cardiovascular outcomes. Little is known about how hemodialysis (HD) parameters acutely influence those biomarkers and prognosis. Objective: To determine if the variation of those biomarkers on the short term is influenced by factors that are already associated with hemodialysisinduced cardiac injury and if it has a prognostic value. Methods: Forty participants undergoing HD at our institution were enrolled. Factors known to influence hs-cTnT and Nt-pro-BNP levels were the principal exclusion criteria. Eight patients were excluded mainly for EF<40%. Six consecutive serum samples were analysed for hs-cTnT and Nt-pro-BNP bef.. Read More»
  

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