Transplantation Technologies & Research

Department of Hematology and Histocompatibility, Amiens University Medical Center, Amiens, France

Publications

• Mini Review   
  Bone Marrow Transplantation Animal Models
  Author(s): Mehdi Bendjelloul*
  
  We combined participant-level data from 524 patients across twenty-two eligible clinical trials that met our inclusion criteria. The type and source of the infused cells had a significant impact on the outcome. 58.9 percent of T1DM patients who received CD34+ hematopoietic stem cell (HSC) infusions became insulin-independent for a mean of 16 months, whereas patients who received umbilical cord blood (UCB) consistently failed. When compared to bone marrow mesenchymal stem cells (BM-MSCs), infusion of umbilical cord mesenchymal stem cells (UC-MSCs) significantly improved T1DM outcomes (P 0.0001 and P=0.1557). Early stem cell therapy administration was more effective than later intervention (relative risk=2.0, P=0.0008) after DM diagnosis. Unfriendly impacts were seen in just 21.72% of both T1DM and T2DM foundational microorganism beneficiaries with no detailed mo.. Read More»
  DOI: 10.37421/2161-0991.2022.12.224

  Abstract HTML PDF