Neurology Department, Hospital Universitario de Burgos, Burgos, Spain
Case Report
New-onset super-refractory status epilepticus following fever: more than a case of NORSE
Author(s): Alicia Hernando-Asensio*, María Asunción Martín-Santidr, Jesús Macarrón-Vicente, Ana Isabel Gómez-Menéndez, Beatriz García-López, Mónica Bártulos-Iglesias and Daniel Pascual-Carrascal
We present the case of a healthy 32-year-old woman who came to our hospital due to fever and left otalgia. She subsequently developed dizziness and gait instability, opsoclonus-myoclonus syndrome, and altered level of consciousness. She was admitted to the intensive care unit, developing status epilepticus, which was refractory to third-line treatment with propofol and barbiturates. A thorough assessment including autoimmunity studies, viral testing, and mitochondrial disease testing yielded negative results. A brain magnetic resonance imaging scan revealed signal hyperintensities in both caudate nuclei and putamina, and gadolinium-enhancing small punctiform lesions in the left hemisphere and left cerebellar tonsil. Suspecting an immune-mediated disorder, we started treatment with high-dose steroids and plasmapheresis, in addition to different combinations of antiepileptic drugs. The .. Read More»
DOI:
10.37421/2329-6895.2020.8.422
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