Department of Biochemistry, Delta University for science and technology, Gamasa, El-Mansoura, Egypt
Research Article
Immunological Study for Helicobacter pylori Bacteria in Human
Author(s): Samuel Tanas Melek*, Mohamed H Yassin, Mohamed E Rashed and Taghreed A Zidan
Helicobacter pylorus is one of the most important human pathogens, infecting more than 50% of the human population. Commonly
the first noninvasively testes used for H. pylori infection's detection were immunological tests like blood antibody test and stool antigen test. We
investigated the more efficient susceptibility immunological test for detection of H.pylori infection in adult Egyptian patients by comparing the
results of H. pylori IgA (HpIgA), IgG in serum blood (HpIgG) and H.pylori Ag in stool (HpSAg) for 30 adult patient (males and females) against
control group using ELISA technique.The results showed that each test could be used successfully for diagnosis of H. pylori with 100%
specificity and PPV% with no gender relation. Finally HpSAg showed reliable results with high sensitivity (>95%) followed by HpIgG
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DOI:
10.37421/2476-1966.2022.7.180
Journal of Immunobiology received 34 citations as per Google Scholar report