Center for Bioinformatics Research, Institute of Systems Biology (INBIOSIS), Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor, Malaysia
Short Communication
Computational Systems Biology Approach on Polycystic Ovarian Syndrome
(PCOS)
Author(s): Afiqah-Aleng N and Mohamed-Hussein ZA*
Polycystic ovarian syndrome (PCOS) is an endocrine disorder that affects women at reproductive age. This
syndrome gives rise to various consequences, from reproductive, dermatological, nervous and psychiatric problems
to different features of metabolic syndrome. Due to the complexity of PCOS, candidate gene approaches are
insufficient to understand its molecular mechanism. A systems biology approach that requires strong integration of
experimental and computational biology to understand the complex biological systems could be used in examining
multiple interacting genes and their products that lead to PCOS. This short communication discusses the available
omics studies that have been conducted in PCOS... Read More»
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