Neurological Disorders

Division of Neurology, Tokuyama Medical Association Hospital, Shunan, Japan

Publications

• Case Report   
  Severe Normal Pressure Hydrocephalus Appearing in the Advanced Stage of Alzheimers Disease: A Case Report
  Author(s): Morimatsu M* and Kawai M
  
  The association of normal pressure hydrocephalus (NPH) with Alzheimer’s disease (AD) is not uncommon. However, we herein report a rare case of AD that showed severe NPH at the late stage of AD. A 74-year-old woman developed forgetfulness without motor disturbances at 56 years old and was diagnosed with AD because of imaging findings showing atrophy of the fronto-temporo-parietal lobes on magnetic resonance imaging (MRI) and a decrease in the regional cerebral blood flow (rCBF) of the frontotemporo- parietal lobes on single-photon emission computed tomography (SPECT). Eight years later, she showed progressive rigidity and akinesia of the arms and legs suggestive of parkinsonism, along with intermittent myoclonus of the arms, both more marked on the right. Her myoclonus was moderately controlled by oral clonazepam. She became bed-ridden at 74 years old and was admitted to our hosp.. Read More»
  DOI: 10.37421/2329-6895.2020.8.418

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