Department of Biotechnology in Health and Investigative Medicine, Gonçalo Moniz Institute, Oswaldo Cruz Foundation/Fiocruz, Salvador, Bahia, Brazil
Commentary
Glycidyl Methacrylate as Probably Carcinogenic to Humans
Author(s): Bruno Jose Dumêt Fernandes*, Silvana Trinchão Costa, Nadielle Silva Bidu and Ricardo David Couto
Glycidyl methacrylate (GMA) is a monomer widely used in the production of dyes, paper, beverages, epoxy polymers, and others. It is a
genotoxic substance with occupational exposure that can reach the general population by inhalation and skin contact. This agent may produce
a large spectrum of DNA damage, evidenced by various carcinogenicity studies conducted on animals, and strong evidence of being
carcinogenic in primary human cells. There is a deficit/absence of studies related to and no threshold limit value for GMA, however, due to
the principles of similarity and precaution, it should be classified as a human carcinogen, and collective and personal control measures should
be implemented or reviewed. This study provides an alert of GMA human exposure and its genotoxic and carcinogenic potential... Read More»
DOI:
10.37421/2161-0525.2021.s6.001
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