Department of Chemistry, University of Sydney, Sydney, Australia
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Isolation and Purification Techniques in Natural Products Chemistry
Author(s): Natalia Perez*
Isolation and purification techniques are fundamental in natural products chemistry, as they enable the extraction of bioactive compounds
from complex biological matrices. This paper provides a comprehensive overview of contemporary methods employed in the isolation and
purification of natural products. It discusses traditional techniques such as solvent extraction, liquid-liquid partitioning, and chromatographic
methods including column chromatography, high-performance liquid chromatography (HPLC), and thin-layer chromatography (TLC). Additionally,
it explores advanced methodologies such as Supercritical Fluid Extraction (SFE), molecularly imprinted polymers (MIPs), and preparative
chromatography. The advantages, limitations, and applications of each technique are analyzed to offer insights into their role in the development
of pharmaceuticals, nutraceuticals,.. Read More»
DOI:
10.37421/2472-0992.2024.10.302
Journal of Pharmacognosy & Natural Products received 606 citations as per Google Scholar report