Department of Chemistry, Benue State Universit,Makurdi, Nigeria
Research Article
Evaluation of the Therapeutic Effects of Telfairia occidentalis as an Adjunct in the Treatment of Malaria with Artemether/ Lumefantrine Regimen in Children with Acute Uncomplicated Malaria
Author(s): Ngoran Shantine Berinyuy, Theresia Njuabe Metoh*, Chi Tchampo Fru, Philip FonGah, Achille Chi Djouosseu, Mabel Kaghou Mbifung, Nina Ghislaine Yensii, Ndi Betrand Bongjo and Carl Moses Mbofung
Malaria, one of the deadliest diseases in Africa, continues to be a public health problem in Cameroon. Malaria management involves the use of
conventional drugs such as Artemether/Lumefantrine (AL), the first drug of choice in the treatment of uncomplicated malaria. Telfairia
occidentalis (pumpkin leaves), a vegetable plant consumed in most parts of the world and with potential antimalarial properties, could serve as
an adjunct therapy in malaria management. This study investigated the therapeutic effect of Telfairia occidentalis on the hemoglobin level,
parasitaemia clearance rate and the liver enzymes activity in children below 16 years. In an open labeled randomized clinical trial, enrolled
participants with P. falciparum malaria and hemoglobin level >5 g/dL were selected to receive either AL+placebo or AL and raw (or boiled)
capsul.. Read More»
DOI:
10.37421/2684-4559.2023.7.216
Clinical Infectious Diseases: Open Access received 49 citations as per Google Scholar report