Department of Medical Biotechnology, University of Gondar, Gondar, Ethiopia
Mini Review
Potential Applications of Genetic Engineered (Transgenic)
Animals in Medical Biotechnology for Human Healthcare
Author(s): Aynias Seid* and Nega Berhane
Genetic engineering is a thoughtful modification process of animal’s genome using recombinant-DNA technology for generating transgenic
animals. Transgenic animals are genetically altered animals having the desired traits. Genetically engineered animals have a significant medical
application for human healthcare by making the transgenic animal models of human disease for studying of gene function; manufacturing of
transplant organs; and production of safe and complex recombinant human protein-based drug, blood and vaccine products with higher expression
and low cost for the treatment and prevention of human disease. The first two commercially accessible therapeutic agents isolated from the milk
of transgenic animals are C1 esterase inhibitor (Ruconest®) and anti-thrombin III (ATryn®), which encourages that a novel recombinant prot.. Read More»
Journal of Bioprocessing & Biotechniques received 3351 citations as per Google Scholar report
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