Journal of Bioprocessing & Biotechniques

Department of Pharmaceutical and Medicinal Chemistry, Nnamdi Azikiwe University, Awka, Nigeria

Publications

• Research Article   
  Hypoglycemic Effect of the Ethyl-Acetate and Butanol Fractions of Mallotus oppostifollous in Mice
  Author(s): Ifeanyi Peter Onyeka*, Valentine Onyeka Nwankwo, Omoirri Moses Aziokpono, Charity C Ezea, Chioma Ifeoma Ibe, Nnamdi Markben Adione, Gabriel Okwudili Ogbuozobe, Ebere Ifejirika Ezeonyi and Chioma Vivian Anidi
  
  A Background: Mallotus oppostifollous is a shrub that has historically been used to cure various ailments including infections, wounds, inflammations, and illnesses linked to oxidative stress in places they occur like South East Nigeria. In the present study the ethyl-acetate and butanol fractions of Mallotus oppostifollous was evaluated for the hypoglycemic and ant hyperglycemic effect using mice. Methods: The dried powdered leaf of M. oppositifolius was extracted by cold maceration using absolute methanol, filtered and dried using rotary evaporator. The dried extract was partitioned into n-hexane, Ethyl Acetate (EAF), Butanol (BF), and Water Fraction (WF) using standard laboratory procedure. Hyperglycemia was induced by intraperitoneal injection of alloxan monohydrate (120 mg/kg) and the animals were observed for.. Read More»
  DOI: 10.37421/2155-9821.2023.13.574

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