Molecular Biomarkers & Diagnosis

Department of Biology, “Alexandru Ioan Cuza” University of Iasi, 700505 Iasi, Romania

Publications

• Mini Review   
  Identification of Misregulated Proteins by Proteomics and Empathy of Biomarkers in Aggressive Ductal Carcinoma
  Author(s): Norman Haaker*
  
  Proteomics is the study of the entire protein complement of an organism, organ, tissue, or biological fluid. Proteomics-based identification of dysregulated proteins and biomarker discovery has become an essential tool for early detection, diagnosis, and treatment of various diseases, including cancer. Invasive ductal carcinoma (IDC) is the most common type of breast cancer, accounting for approximately 80% of all breast cancers. Proteomics-based approaches have been used to identify dysregulated proteins and biomarkers in IDC, which can potentially improve early detection, diagnosis, and treatment. MS is a technique that can be used to identify proteins based on their mass-to-charge ratio. Proteins are first digested into peptides using a protease such as trypsin. The resulting peptides are then ionized and introduced into the mass spectrometer. The mass spectrometer separates the pe.. Read More»
  DOI: 10.37421/2155-9929.2023.14.570

  Abstract HTML PDF