University Hospital Careggi, Florence, Italy
Research Article
Whole-Body MRI and Whole Body [123I]-I-mIBG Scintigraphy: a Comparison in Intermediate and High Risk Neuroblastoma and validation of SIOPEN Scoring System in WB-MRI
Author(s): Olianti C*, Perrone A, Allocca M, Di Maurizio M, Carra F, La Cava G and Tondo A
Purpose: To assess the agreement between 123I-metaiodobenzylguanidine or [123I]-I-mIBG and Whole Body Magnetic Resonance Imaging with
diffusion-weighted whole-body imaging with background body signal suppression (WB MRI-DWIBS) in High and Intermediate risk Neuroblastoma,
a retrospective review was performed on [123I]-I-mIBG and DWIBS paired scans acquired at diagnosis, response-to-therapy, after-surgery, off
therapy and after relapse with systemic involvement, and osteo-bone marrow metastatic load was evaluated for each of them.
Methods: 80 paired [123I]-I-mIBG and DWIBS scans were acquired for 31 patients between June 2009 and June 2019 within 30 days and
without intercurrent therapy. SIOPEN Semi-quantitative Scoring Systems for NB with 12 body sections was applied at whole body MIBG and WB
MRI-DWIBS acquired to evaluate the .. Read More»
DOI:
10.37421/1747-0862.2021.15.505
Molecular and Genetic Medicine received 3919 citations as per Google Scholar report