Archives of Surgical Oncology

Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA

Publications

• Mini Review   
  Revolutionizing Postoperative Cancer Care: A Poly(I:C) Hydrogel's Impact on Recurrence Prevention and Immunomodulation
  Author(s): Paul Lawrenson*
  
  The postoperative period following cancer surgery is a pivotal juncture in a patient's path to recovery, fraught with the specter of cancer recurrence. To address this critical challenge, innovative strategies are now at the forefront of cancer care. This article delves into groundbreaking research, unveiling a surgically optimized poly(I:C) hydrogel that not only prevents postoperative cancer recurrence but does so through a unique and promising mechanism. By harnessing the interferon-alpha (IFNα) response, attracting inflammatory monocytes, and depleting regulatory T cells (Tregs), this hydrogel emerges as a potential game-changer in the prevention of postoperative cancer recurrence. We scrutinize the significance of these findings and their potential to reshape the landscape of postoperative cancer care, offering newfound hope and assurance to patients in .. Read More»
  DOI: 10.37421/2471-2671.2023.9.68

  Abstract HTML PDF