Department of Cytogenetics, Lorraine University, F-54000 Nancy, France
Mini Review
Employing Humanized Gnotobiotic Rats: Unveiling Nutritive and Oxidative Consequences of Mediterranean Diet and Oilbased Supplements on Cardiovascular and Metabolic Disorders through Multi−omics Research
Author(s): Peter Blackwood*
The Mediterranean diet, renowned for its health-promoting effects, has long been associated with a reduced risk of cardiovascular and metabolic
disorders. In recent years, advancements in multi-omics research have allowed scientists to delve deeper into the intricate mechanisms underlying
these benefits. Employing humanized gnotobiotic rats as a model system, this study aims to elucidate the nutritive and oxidative consequences of
a Mediterranean diet and oil-based supplements on cardiovascular and metabolic health. By integrating genomics, transcriptomics, proteomics,
and metabolomics data, researchers are gaining unprecedented insights into the molecular pathways influenced by dietary interventions. This
article reviews the current understanding of the Mediterranean diet, the significance of employing humanized gnotobiotic rats in research, and the
insights g.. Read More»
DOI:
10.37421/2952-8100.2023.6.427
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