Department of Biotechnology, Macquarie University, North Ryde, NSW 2109, Australia
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Metal Detection Biosensor Using Enhanced Green Fluorescent Protein Platform
Author(s): Philip Gomes*
The development of sensitive and efficient biosensors for metal detection is of paramount importance for various applications including environmental monitoring, food safety and medical diagnostics. This study presents a novel approach using an Enhanced Green Fluorescent Protein (EGFP) platform as the foundation for a metal detection biosensor. By fusing EGFP with metal-binding peptides, the biosensor achieves enhanced specificity and sensitivity for targeted metal ions. The biosensor operates based on the principle that metal ions bind to the modified EGFP, inducing changes in its fluorescence emission spectrum. These alterations in fluorescence properties serve as quantifiable indicators of metal presence and concentration. The versatility of EGFP as a platform enables the development of biosensors tailored to detect specific metal ions, offering flexibility in addressing diverse me.. Read More»
DOI:
10.37421/2155-6210.2023.14.403
Biosensors & Bioelectronics received 1751 citations as per Google Scholar report