Huxley Faculty Fellow, Department of Ecology and Evolutionary Biology, Rice University, USA
Short Communication
A framework for alternative ways of looking at biodiversity
Author(s): Phillip Andrew*
Phylogenetics is the study of the evolutionary relatedness among groups of organisms. Molecular phylogenetics uses sequence data to infer these relationships for both organisms and the genes they maintain. With the large amount of publicly available sequence data, phylogenetic inference has become increasingly important in all fields of biology. In the case of natural product research, phylogenetic relationships are proving to be highly informative in terms of delineating the architecture and function of the genes involved in secondary metabolite biosynthesis.
Polyketide syntheses and non-ribosomal peptide syntheses provide model examples in which individual domain phylogenies display different predictive capacities, resolving features ranging from substrate specificity to structural motifs associated with the final metabolic product. This chapter provides examples in which ph.. Read More»
Journal of Phylogenetics & Evolutionary Biology received 911 citations as per Google Scholar report