Hepatology and Pancreatic Science

Department of Pharmaceutical Engineering and Technology, Banaras Hindu University, Varanasi, Uttar Pradesh, India

Publications

• Research Article   
  Drug induced liver toxicity-where we are?
  Author(s): Santosh Nagare* and Prasanta Kumar Nayak
  
  Drugs are the one of the major cause of liver injury. Because with some exception all drugs are metabolized by the liver it carries inherent risk of injury or toxicity. Various Xenobiotics by various ways affect the liver, many drugs produces acute liver injury that liver may repair itself because of its fast regenerating property. DILI classified as acute, Idiosyncratic and chronic on the basis of there mechanism and duration of toxicity. Some common agents that can cause liver injury are acetaminophen, antibiotics, statins, INH and herbal drugs with different modes and duration to affect the liver. Many drugs not affect the liver when taken for short duration but on continuous consumption they leads to disruption of hepatocytes. The obvious fact that different drug utilises different enzymes to get metabolised the toxicity produced by them also varies. The li.. Read More»
  

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