Clinical and Medical Case Reports

Crops Technology Research Department, Food Technology Research Institute, Agricultural Research Center, Giza, Egypt

Publications

• Research Article   
  Curcumin (Curcuma Longa) and Quercetin Nanoparticles as Anticancer Agents for HepG2 and HCT116 Human Cell Lines
  Author(s): Soheir N. Abd El-Rahman* and Raafat N. Sandak
  
  Curcumin and quercetin are very poor water solubility, it could be these bio products useful and important in condition therapy related with cancer, oxidative stress and can used it to develop functional foods and to improve the foods shelf life. The objective was to prepare Curcumin and quercetin nanoparticles (CurNPs and QurNPs) give highly stable and soluble in water. The DPPH radical scavenging activity, HepG2 and HCT116 human cell lines (human cancer liver and colon) and antimicrobial of CurNPs and QurNPs were determined. The results showed that the CurNPs and QurNPs had the highest DPPH free radical scavenging activity at concentrate 1000 µg/ml were 94.91 and 98.11%, these results equal or nearly from ascorbic acid as at positive control at the same concentrate was 98.69%. CurNPs and QurNPs were significantly increased cell cytotoxicity, from the minimum to maximum concent.. Read More»
  DOI: 10.37421/cmcr.2021.5.166

  Abstract HTML PDF