Journal of Bioengineering & Biomedical Science

Department of Zoology, University of PMAS Arid Agriculture, Punjab, Pakistan

Publications

• Research Article   
  Association of MTHFR C677T with Obesity in Human Female Population
  Author(s): Rakhshanda Rani* and Muhammad Irfan
  
  The hypothalamo-pituitary-thyroid axis is responsible for the maintenance of the metabolic processes in the human body. The hypothalamus releases Thyroid Releasing Hormone (TRH) which stimulates the pituitary gland to release Thyroid Stimulating Hormone (TSH) which in turn leads to stimulation of the thyroid gland and release of Thyroxine (T4) and its active derivative Triiodothyroxine (T3). Malfunctioning of any component at any level of the hierarchy of the axis may lead to disorders of metabolism including obesity. The Thyrotropin Releasing Hormone (TRH) is a hypothalamic peptide hormone that possesses a broad spectrum of effects mainly determined by its stimulatory effects on energy metabolism together with iodine containing hormones of the thyroid. The objective of this study is to determine association of a specific Mthfr single nucleotide polymorphism wi.. Read More»
  DOI: 10.37421/2155-9538.2023.13.366

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