Journal of Diabetic Complications & Medicine

Department of Medicine, University of Washington, Washington, United States

Publications

• Research Article   
  Cyclosporine Nephrotoxicity in Patients with Type 1 Diabetes Mellitus Arbitrary Verdict: A Meta-Analysis of Randomized Control Trials
  Author(s): Ahmed M El-Malky* and Ramachandra G Naik
  
  Background: Disturbance in renal function was considered to be a common complication of Cyclosporine-A (CsA) treated patients of recent-onset type 1 diabetes mellitus, for purposes of remission. The aim of the present study was to scrutinize the potential association between this drug and its complications by conducting a meta-analysis of randomized control trials. Methods: A consummate literature search of PubMed, EMBASE, and web of science was conducted until March 2019. A total of 9 randomized control trials were included in this meta-analysis. Results: On meta-analysis of nine studies evaluating the risk of transient complications, analysis of the random effect of 12 months-low dose-cyclosporine on serum creatinine, revealed the absence of CsA induced nephrotoxicity. And no association between CsA and r.. Read More»
  DOI: 10.37421/2475-3211.2023.8.205

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