Department of Restorative Sciences and Biomaterials, Boston University, United States
Review
Stimulatory Role of Magnesium Chloride in Expression of Dentin Matrix Proteins
Author(s): Rania M Salem*, Chang Zhang and Laisheng Chou
Magnesium-based biomaterials might provide an innovative therapeutic potential to substantially enhance regeneration of dental tissues. In previous work,
magnesium oxide (MgO) has been studied for its potential ability to enhance cell attachment, proliferation rate and dentin matrix protein expression of human
dental pulp cells (HDPCs). However, to date, dentinogenic effect of magnesium chloride (MgCl2) on cell viability and expression of extracellular matrix proteins
in HDPCs has not been investigated. This study was designed to compare the stimulatory effect of different concentrations of MgCl2 on dentinogenesis of
HDPCs. HDPCs were cultured with 0.5 mM, 1 mM, 2 mM, 4 mM, 8 mM concentrations of supplemental MgCl2, 0 mM as negative control group. Stimulatory effect
of MgCl2 was assessed by evaluating cell viability, and expre.. Read More»
DOI:
10.37421/jme.2022.11.618
Journal of Material Sciences & Engineering received 3677 citations as per Google Scholar report
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