Department of Radiology, King Abdul Aziz University Hospital, Saudi Arabia
Research
Re-Irradiation for Recurrent Brain Tumors: A Retrospective Study from a Tertiary Hospital in Saudi Arabia
Author(s): Hafiz Asif Iqbal*, Rolina K. Alwassia, Zaheeda Mulla, Ahmed AbdelKhalek Hussein and Hane Mohammad Muamenah
Objective: To analyze the post-re-RT progression-free survival (PFS) and incidence of radio-necrosis (BRN) in patients with recurrent primary brain tumors and to explore the associated factors.
Method: A retrospective cohort study that included 15 pediatric and adult patients with primary brain tumors who were treated with re-RT between 2011 and 2020. The study endpoints included the post-re-RT PFS, which were analyzed using Kaplan-Meier survival analysis, and the incidence of radio-necrosis. Baseline demographic and clinical data, primary radiation therapy (RT1) parameters and outcomes, and re-RT parameters and outcomes, were analyzed as factors for the two outcomes.
Result: Of the 15 participants, 7 had glioblastoma and 5 had anaplastic ependymoma. The mean interval from first RT to re-RT was 24 months (range=2-6.. Read More»
DOI:
10.4172/2329-6895.10.2.477
Neurological Disorders received 1343 citations as per Google Scholar report