Chemical Sciences Journal

Department of Chemical Science, Acharya Nagarjuna University, Guntur, India

Publications

• Commentary   
  Analytical Method for Determination of Amphotericin
  Author(s): S Lakshmi Swamy*
  
  By utilising RP-HPLC with UV detection, a straightforward, sensitive, and precise analytical has been established to estimate amphotericin in pharmaceutical effluents that the pharmaceutical industry are discharging into aquatic environments. The devised approach is extremely accurate and sensitive to detect amphotericin at concentrations of less than 0.1ppm-5ppm. For the measurement of Amphotericin in effluents or pharmaceutical industry washouts, a reversed-phase high performance liquid chromatography (RP-HPLC) method was created and validated. On a Symmetry C-18 column (250mm 4.6mm i.d., 5.0m), the separation was accomplished using a citrate buffer with a pH of 4.5 as the buffer, and a combination of 400mL buffer and 600mL acetonitrile in isocratic mode as the mobile phase, all at a flow rate of 1.2 mL/min. A UV detector operating at 383 nm was used for dete.. Read More»
  DOI: 10.37421/2150-3494.2022.13.307

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