Journal of Sports Medicine & Doping Studies

Department of Medicine and Health Sciences, Andrzej Frycz Modrzewski Krakow University, 30-705 Kraków, Poland

Publications

• Mini Review   
  Unravelling the Effects of Indomethacin on Steroid Metabolism: Implications for Endocrine Disruption and Urinary Steroid Profiling in Anti-Doping Analyses
  Author(s): Sara Baglio*
  
  Indomethacin, a commonly used non-steroidal anti-inflammatory drug, has been shown to potentially impact steroid metabolism, leading to implications for endocrine disruption and urinary steroid profiling in anti-doping analyses. This abstract presents a summary of the effects of indomethacin on steroid metabolism and its broader implications. Studies investigating the influence of indomethacin on steroid-metabolizing enzymes have demonstrated alterations in enzymatic activity, which can disrupt the normal balance of steroid hormones in the body. Consequently, these disruptions can have implications for urinary steroid profiling, potentially leading to false-positive or false-negative results in anti-doping testing. Understanding the effects of indomethacin on steroid metabolism is crucial for accurate interpretation of urinary steroid profiles in antidoping ana.. Read More»
  DOI: 10.37421/2161-0673.2023.13.309

  Abstract HTML PDF