Molecular and Genetic Medicine

Laboratory of Molecular Biology, Military hospital of Ouakam (HMO), Dakar, Senegal

Publications

• Research Article   
  Comparison of Roche COBAS^®AmpliPrep/COBAS^®TaqManHIV-1v2.0 and Abbott m2000sp/m2000rt for the Measurement of HIV-1 Viral Load in Senegal
  Author(s): Faye B*, Dieng FB, Charlebois R, Sarr H, Diouf SG, Diagne MM, Sembène M and Dièye A
  
  Accurate quantification of HIV-1 viral load (VL) is crucial for assessing infection stage and efficacy of antiretroviral therapy (ART). Despite recommendations for measuring VL amongst people living with HIV, the accessibility and availability of this parameter remain low in resource-limited settings, primarily due to the lack of qualified human resources and necessary reagents. Solutions must be found to help developing countries attain the Joint United Nations Program on HIV/AIDS (UNAIDS) 90-90-90 targets for 2020. This study was designed to compare the quantification of HIV-1 VL between two reverse transcriptase real-time PCR techniques: RocheCOBAS® AmpliPrep/ COBAS®TaqMan®HIV-1v2.0 and Abbott m2000sp/m2000rt. To conduct the comparison, 231 samples for VL were assessed. Samples were stratified according to the.. Read More»
  

  Abstract HTML PDF