Journal of Oncology Medicine & Practice

Department of Cancer Biology and Nanotechnology, University of Singapore, Queenstown, Singapore

Publications

• Mini Review   
  Angiogenesis, the Tumour Microenvironment and Proteoglycans in Cancer Biology
  Author(s): Seeram Ramakrishna*
  
  Angiogenesis, the tumour microenvironment, and proteoglycans play pivotal roles in cancer biology. Angiogenesis, the formation of new blood vessels, is a critical process for tumour growth and metastasis. The tumor microenvironment, consisting of various cellular and non-cellular components, provides a supportive niche for cancer progression. Proteoglycans, a class of complex molecules, are involved in modulating both angiogenesis and the tumour microenvironment. Angiogenesis in cancer is driven by a delicate balance of pro-angiogenic and anti-angiogenic factors. Tumour cells release pro-antigenic factors, such as Vascular Endothelial Growth Factors (VEGFs), to stimulate the sprouting of new blood vessels from existing vasculature. The tumour microenvironment, including immune cells, fibroblasts, and extracellular matrix components, also contributes to angiogen.. Read More»
  DOI: 10.37421/2576-3857.2023.08.196

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