Department of Medicine, University of Miami, Gorgan, Iran
Mini Review
Comparing the Clinical Efficacy of Posaconazole and Fluconazole as Antifungal Prophylaxis in the Field of Hematology
Author(s): Seid Jafari*
This study aims to compare the clinical efficacy of posaconazole and fluconazole as antifungal prophylaxis in the field of hematology.
Antifungal prophylaxis plays a crucial role in preventing invasive fungal infections, which are a significant cause of morbidity and mortality in
immunocompromised patients, particularly those undergoing Hematopoietic Stem Cell Transplantation (HSCT) or intensive chemotherapy. A
comprehensive literature review was conducted to identify relevant studies comparing the clinical outcomes of posaconazole and fluconazole
prophylaxis in hematology patients. The primary endpoints assessed were the incidence of IFIs, overall survival, and adverse events associated
with each antifungal agent. The results of the reviewed studies demonstrated that posaconazole had superior efficacy compared to fluconazole in
preventing IFIs in hematology pa.. Read More»
DOI:
10.37421/2576-3857.2023.08.198
Journal of Oncology Medicine & Practice received 142 citations as per Google Scholar report