Environmental & Analytical Toxicology

Department of Public Health, Institut Kesehatan Deli Husada Deli Tua, Deli Tua Timur, Deli Tua, Deli Serdang, Sumatera Utara, 20355, Indonesia

Publications

• Research Article   
  Physicochemical, Pharmacokinetics, and Toxicity of South Africa Leaf (Vernonia amygdalina Delile) Sesquiterpene Lactone Compounds by In Silico
  Author(s): Nerdy Nerd*, Linda Margata, Bunga Rimta Barus, Bunga Mari Sembiring, Selamat Ginting and Tedy Kurniawan Bakri
  
  Cancer is a disease caused by malignant growth that can occur in humans, animals and plants. Cancer treatment with chemotherapeutic agents is still the main option in cancer treatment. Various efforts to develop new treatment methods are needed for more effective cancer therapy one of them is cyclophosphamide. The sesquiterpene lactone compounds contained in South Africa Leaf (Vernonia amygdalina Delile) contribute to its pharmacological effects as anticancer for several cancers. This study aims to determine the pharmacokinetic profile and toxicity profile of various sesquiterpene lactone compounds contained in South Africa Leaf (Vernonia amygdalina Delile). This research begins with a search for the physicochemical properties and Canonical Simplified Molecular Input Line Entry System (SMILES) code with the assisted of the P.. Read More»
  DOI: 10.37421/2161-0525.2021.s7.002

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