Malaria Control & Elimination

Department of Epidemiology, Mahidol University, Bangkok, Thailand

Publications

• Mini Review   
  Exploring Novel Parasite Ligands as Vaccine Antigens to Target the Plasmodium Life Cycle
  Author(s): Shan Khan*
  
  Malaria continues to pose a significant global health threat, necessitating the development of effective vaccines to complement existing control measures. Recent advancements in our understanding of Plasmodium parasite biology have identified novel parasite ligands as promising vaccine antigens to target the complex life cycle of the parasite. These parasite ligands, expressed on the surface of Plasmodium parasites, play crucial roles in host cell invasion, immune evasion, and disease pathogenesis. By targeting these ligands, vaccines aim to induce immune responses capable of preventing parasite invasion, blocking transmission, or eliminating infected cells. This article explores the potential of selected novel parasite ligands, including Apical Membrane Antigen 1, Circumsporozoite Protein, Thrombospondin-Related Anonymous Protein and Rhoptry Neck Protein 2, as.. Read More»
  DOI: 10.37421/2470-6965.2024.13.284

  Abstract HTML PDF