Molecular and Genetic Medicine

Department of Cardiology, Clinical College of Yangtze University and the First Affiliated Hospital to Yangtze University, Jingzhou, Hubei, P.R. China

Publications

• Review Article   
  Atrial Fibrillation Associated with Wolf-Parkinson-White Syndrome in Patients with Brugada Syndrome: A Review
  Author(s): Goit LN*, Shaning Y and Wang X
  
  The Brugada syndrome is an autosomal dominant rare form of cardiac arrhythmia and has been associated with high risk of sudden cardiac death predominantly in younger male patients. It is associated with polymorphic ventricular arrhythmia/ventricular fibrillation, Supraventricular arrhythmia mainly atrial fibrillations and Wolf- Parkinson white syndrome. Patients can be presented with symptom like syncope, palpitation, sudden cardiac death and asymptomatically. Several pathogenic genes have been identified as associated with the disease but SCN5A is the most prevalent one. Several genetic mutations of different subunits of sodium, calcium and potassium channel have been involved. The management of Brugada syndrome and Wolf-Parkinson-White syndrome in patients with atrial fibrillation should be generally includes implantable cardioverter defibrillator and Rad.. Read More»
  

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