Journal of AIDS & Clinical Research

Department of Molecular Medicine and Pathology, University of Auckland, Auckland 1010, New Zealand

Publications

• Research   
  Increased Mean Corpuscular Volume and Macrocytosis Associated With the Use of Emtricitabine or Lamivudine in People Living With HIV Infection
  Author(s): Amelia Shin*, Eamon Duffy, Nicola Eaddy and Simon Briggs
  
  Many people living with Human Immunodeficiency Virus (HIV) infection receive treatment with nucleoside reverse transcriptase inhibitors. This study’s objective was to evaluate whether treatment with lamivudine and emtricitabine can result in an elevated Mean Corpuscular Volume (MCV). This was a retrospective cohort study of people who were newly diagnosed with HIV infection and received treatment with lamivudine and/or emtricitabine. MCV is already a part of blood tests routinely performed in the care of people living with HIV infection. This study evaluated a difference in individual person’s MCV from prior to their anti-retroviral treatment (ART) and post-ART. Between January 2011 and June 2020, 282 people were newly diagnosed with HIV infection. 226 (80%) received emtricitabine, 45 (16%) received lamivudine and 11 (4%) received emtricitabine and lamivudine s.. Read More»
  DOI: 10.37421/2155-6113.2024.15.1021

  Abstract HTML PDF