Journal of Forensic Research

Laboratoire de Police Scientifique de Lyon, Service National de Police Scientifique, Ecully, France

Publications

• Research Article   
  DNA Methylation-based Age Prediction from Blood Samples of French Child and Adult Individuals
  Author(s): Camille Ropert, Simon Buré, Adèle Sourisce, Caroline Gallois, Myriam Siffointe, Laurent Bartholin, Fabrice Besacier, Romain Appourchaux and Mathieu Gabut*
  
  Objective: Identifying the origin of human biological traces detected at crime scenes by comparing DNA profiles to national or international forensic databases is often key to provide new orientations to police investigations. However, when unknown profiles are established, investigators can benefit from forensic genetics to propose new leads, for example by predicting the physical appearance of individuals. Since blood traces are of primary interest for forensic investigators and often lead to the extraction of usable genetic material, in this study, we developed a methodology to predict the biological age from blood samples based on the analysis of DNA methylation of human genomic regions. Methods: We first established a cohort of blood samples obtained from 170 French donors aged from 0 to 101 years old. We analyzed the methylation status.. Read More»
  DOI: 10.37421/2157-7145.2024.15.606

  Abstract HTML PDF