Clinical and Medical Case Reports

Department of Internal Medicine, Faculty of Medicine, Inonu University, Malatya, Turkey

Publications

• Case Report   
  Toxic Hepatitis Due To Ingesting Ferula Communis (Giant Fennel); Case Series
  Author(s): Caliskan AR*, Harputluoglu MMM, Slocum A, Kutlu R and Yilmaz S
  
  Awareness of the potential hepatotoxic effects of herbal preparations and dietary supplements is increasing. The drug-induced liver injury network (DILIN) states that herbal and dietary supplements (HDS) account for 16% of DILI cases, and this rate, which was 7% in 2004-2005, is estimated to increase to 20% in 2013-2014. In our series of 6 cases, 5 of the patients were from the same family, and there was a 4-month pregnant patient. One day after eating ferula communis, the patients were taken to the emergency room due to nausea, vomiting, and abdominal pain. The current hepatitis tables were evaluated as the hepatocellular pattern. Intravenous (i.v.) hydration and acetylcysteine 3x1 ampule iv. were administered to the patients. Two sessions of plasmapheresis were performed for one of the patients who had a presentation of fulminant hepatitis. An improvement was observed in the clinica.. Read More»
  

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